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PRK vs LASEK vs Epi-LASIK: A comparison of corneal haze, postoperative pain and visual recovery in moderate to high myopia.
Nepal J Ophthalmol. 2010 Jul;2(4):97-104. doi: 10.3126/Nepal Ophthalmic Society.v2i2.3715.
Reilly CD, Panday V, Lazos V, Mittelstaedt BR.
SourceWilford Hall, Warfighter Refractive Surgery Center, San Antonio, TX, USA.

Introduction: The field of refractive surgery continues to evolve amid continued concerns as to which surgical technique minimizes the risk of inducing ectasia. Purpose: To compare clinical outcomes between PRK, LASEK and Epi-LASIK in moderately to highly myopic eyes (-4.00 D to -8.00 D). Materials and methods: A retrospective chart review of 100 PRK eyes, 100 LASEK eyes (with alcohol) and 97 Epi-LASIK eyes was performed. Post-operative pain, uncorrected visual acuity, and corneal haze data was recorded and analyzed at post-op days 1, 4 and 7 and at post-op months 1, 3, 6 and 12. Results: In all groups surgical corrections ranged from -4.00 D to -8.00 D. There was less pain associated with the epi-LASIK procedure especially early (post-op days 1 and 4). Visual recovery was superior within the PRK group during the first post-operative week but by post-op week 4 all three were equal. Haze scores were similar but a trend for less haze was demonstrated with epi-LASIK at 6 and 12 months. Conclusion: Epi-LASIK has a slight advantage over PRK and LASEK early on in the post-op course with regards to pain. Visual recovery is similar by 4 weeks and is better with PRK early. In addition, epi-LASIK trends toward less significant haze.

　　這份臨床對(duì)比研究于2010年7月發(fā)表于尼泊爾眼科雜志?；仡櫡治隽?00只PRK手術(shù)眼，100只LASEK手術(shù)眼和97只Epi-LASIK手術(shù)眼術(shù)后疼痛，裸眼視力，角膜haze情況，治療的度數(shù)在-400度到-800度之間，觀察時(shí)間為術(shù)后1天，4天，7天，術(shù)后1月，2月，6月，12月。結(jié)果顯示Epi-LASIK術(shù)后疼痛最輕，視力恢復(fù)情況三者差不多，Epi-LASIK術(shù)后haze更輕微。

                                                                       （黃正 譯）