
探尋Amadeus II微型角膜刀制作高質(zhì)量角膜瓣的最佳參數(shù)設(shè)置
Amadeus II microkeratome: optimizing microkeratome settings for high flap accuracy using optical low coherence reflectometry.
Eur J Ophthalmol. 2010 Jan-Feb;20(1):41-7.
Lackerbauer CA, Kollias A, Kreutzer TC, Ulbig M, Kampik A, Grueterich M.
Source
Department of Ophthalmology, Ludwig-Maximilians-University, Munich - Germany. Carlo.Lackerbauer@med.uni-muenchen.de
Abstract
PURPOSE:
To investigate the impact of various experimental microkeratome settings and blade reuse on the accuracy of the flap thickness created with the new Amadeus II microkeratome (SIS, Ziemer Ophthalmic, Port, Switzerland).
METHODS:
In this prospective study, 120 porcine eyes were used to create corneal flaps with the Amadeus II using 2 different cutting heads (140 microm, 160 microm) with the Surepass blade. Using each blade twice, a head advance speed of 1.5 mm/s and 3.5 mm/s and oscillation rates of 8000 rpm, 10,000 rpm, and 13,000 rpm were used. Flap thickness was measured by optical low coherence reflectometry (OLCR). Descriptive statistical analysis was based on means, medians, and quartiles, with graphical representation on box plot. Pearson correlation test and Mann-Whitney U-test for unpaired samples were employed to identify the impact of different settings.
RESULTS:
Using the 140 microm cutting head, highest precision of the flap thickness was achieved with a head advance rate of 1.5 mm/s and an oscillation rate of 10,000 rpm (mean 132.1+/-10.0 microm; range 120.2-147.2 microm). Reusing the blade, highest accuracy (mean 130+/-6.9 microm; range 118.5-135 microm) was achieved with 8000 rpm. Using the 160 microm cutting head, an optimum flap thickness was reached with a head advance rate of 3.5 mm/s and an oscillation rate of 13,000 rpm (mean 162.4+/-7.7 microm; range 151.9-169.8 microm). Reusing the blade with the 160 microm cutting head, an adjustment to 3.5 mm/s and 10,000 rpm was necessary (mean 157.4+/-7.7 microm; range 153.7-161.8 microm).
CONCLUSIONS:
Optimized microkeratome settings lead to minimized deviation from the intended flap thickness and are mandatory to improve flap accuracy. OLCR is an ideal method to proof individualized settings.
這項(xiàng)研究于2011年1月發(fā)表于歐洲眼科學(xué)雜志上,旨在探尋Amadeus II微型角膜刀制作高質(zhì)量角膜瓣的最佳參數(shù)設(shè)置。在這個(gè)前瞻性研究中,120個(gè)豬眼被用于制作角膜瓣。分別采用2個(gè)刀頭(140um和160um),每個(gè)刀片用兩次(相當(dāng)于一個(gè)人的兩只眼),前進(jìn)速度分別為1.5mm/s和3.5mm/s,振動(dòng)頻率分別為8000轉(zhuǎn)/m,10000轉(zhuǎn)/m,13000轉(zhuǎn)/m。利用光學(xué)低相干反射生物測量儀測量角膜瓣的厚度。結(jié)果顯示,用140um刀頭,最精確角膜瓣厚度參數(shù)為前進(jìn)速度1.5mm/s,振動(dòng)頻率10000轉(zhuǎn)/m,此刀片第二次使用時(shí),最佳參數(shù)為振動(dòng)頻率8000轉(zhuǎn)/m。用160um刀頭,最佳參數(shù)為前進(jìn)速度3.5mm/s,振動(dòng)頻率13000轉(zhuǎn)/m,第二次使用刀片時(shí),最佳參數(shù)為前進(jìn)速度3.5mm/s,振動(dòng)頻率10000轉(zhuǎn)/m。
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