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3種飛秒激光和一種角膜刀制作角膜瓣的對(duì)比研究
Comparison of laser in situ keratomileusis flaps created by 3 femtosecond lasers and a microkeratome.
J Cataract Refract Surg. 2011 Feb;37(2):349-57.
Ahn H, Kim JK, Kim CK, Han GH, Seo KY, Kim EK, Kim TI.
Source
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

Abstract
PURPOSE:
To evaluate the thickness and side-cut angle of laser in situ keratomileusis (LASIK) flaps created by 1 of 3 femtosecond lasers or a microkeratome using Fourier-domain optical coherence tomography (OCT).

SETTING:
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

DESIGN:
Comparative case series.

METHODS:
Flap creation for bilateral LASIK was performed using an IntraLase (femtosecond group 1), VisuMax (femtosecond group 2), or Femto LDV (femtosecond group 3) femtosecond laser or an M2 microkeratome. Flap thickness was determined at 14 points. The side-cut angle was measured in 4 directions at the margin interface. Measurements were taken 2 months postoperatively using an RTVue Fourier-domain OCT device and integrated software.

RESULTS:
Femtosecond group 1 comprised 50 eyes; femtosecond group 2, 40 eyes; femtosecond group 3, 64 eyes; and the microkeratome group, 52 eyes. Eyes in femtosecond groups 1 and 2 had relatively even flap configuration. Flaps in femtosecond group 3 and the microkeratome group had a meniscus shape. Flaps in femtosecond group 1 had the least difference between the mean peripheral and the central flap thickness (P<.001). The greatest flap thickness predictability (measured versus intended thickness) was in femtosecond group 3 (P<.001). Flaps in femtosecond group 1 had a side-cut angle closest to 90 degrees (P<.001).

CONCLUSIONS:
Flap morphology differed according to the system used. The 3 femtosecond laser systems appeared to be superior to the microkeratome system generally. The 3 femtosecond laser systems also produced different flap configurations depending on their individual mechanisms.

　　這項(xiàng)研究于2011年2月發(fā)表于白內(nèi)障眼屈光雜志，該研究利用前節(jié)OCT對(duì)比分析了intralase飛秒激光，蔡司VisuMax飛秒激光，瑞士達(dá)芬奇飛秒激光和M2角膜刀制作角膜瓣的厚度和瓣緣角度。結(jié)果顯示，intralase飛秒激光和蔡司VisuMax飛秒激光能夠制作比較均一的角膜瓣，而瑞士達(dá)芬奇飛秒激光和M2角膜刀制作的角膜瓣為新月形（即角膜瓣中央薄邊緣厚）。intralase飛秒激光制作的角膜瓣中央和邊緣的厚度差異最小（即角膜瓣厚度最均一）。瑞士達(dá)芬奇飛秒激光制作角膜瓣厚度的預(yù)測(cè)性最好，而intralase飛秒激光瓣緣角度的可控性最好。
編譯者注：intralase飛秒激光制瓣厚度為90μm-400μm, 以1μm增減，邊切角度30-90°，以1°增減，瑞士達(dá)芬奇飛秒激只能做3個(gè)厚度90μm、110 μm、140 μm，邊切角度固定28°
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